The St. James Guide to Black Artists describes Artis Lane's sculpture as "primarily concerned with portraying what she sees as enduring spiritual truths. These truths are that the growth of spiritual awareness is continuous and that nobody ever arrives at perfection. In addition, spiritual awareness connects humans with a universal force."
Her commissions include a series of bronze portraits for the Soul Train Awards, a bronze portrait of Rosa Parks for the Smithsonian Institution and designing the original logo for the Dance Theatre of Harlem. She has made sculptures of prominent people as former President George H. W. Bush, Bill Cosby, Walter Annenberg, Michael Jordan, Gordon Getty, Nelson Mandela and Henry Kissinger.